The San Francisco 49ers will face off against the Minnesota Vikings at 1:00 ET on Sunday, September 15th. This matchup is being played at U.S. Bank Stadium in Minneapolis.

The 49ers are favored on the road as they face off against the Vikings at 1:00 ET on Sunday, September 15th at U.S. Bank Stadium in Minneapolis. The game is being televised on CBS. The 49ers’ money line odds are -267, while the Vikings are at +216. The 49ers are favored by -6 points, and the over/under line is set at 45.5 points.

• Date: Sunday, September 15th
• Time: 1:00 ET
• Location: U.S. Bank Stadium, Minneapolis
• TV: CBS

49ers vs Vikings

The 49ers are now 1-0 after a 32-19 win over the Jets. San Francisco was favored by -3.5 and covered the spread with their 13-point victory. The combined 51 points exceeded the O/U line of 43.5 points.

Jake Moody’s 53-yard field goal in the 3rd quarter and a late 3-yard touchdown from Tyrod Taylor to Allen Lazard were the only scores in the 4th quarter. The 49ers took the lead for good in the 2nd quarter with two touchdowns, one from Brock Purdy to Jauan Jennings and another from Deebo Samuel. The Jets scored first with a 3-yard touchdown run from Breece Hall in the 1st quarter, but the 49ers led 16-7 at halftime.

Minnesota’s 28-6 victory over the Giants saw them pull away in the 3rd quarter after leading 14-3 at halftime. The Vikings started the game by giving up a field goal but responded with a 3-yard rushing touchdown by Aaron Jones. From there, Minnesota added a touchdown in the 2nd quarter and two more in the 3rd quarter, including a 44-yard touchdown pass from Sam Darnold to Justin Jefferson and another touchdown pass from Darnold to Johnny Mundt.

The Vikings’ defense also played well, holding the Giants to just a field goal in the 3rd quarter and a field goal in the 2nd. With the 28-6 win, the Vikings covered the spread as -1 point favorites on the road, and the game finished with a combined 34 points, falling short of the over/under line of 42 points.

49ers Injury Report

• Christian McCaffrey – Calf/achilles (Out)
• Jon Feliciano – Undisclosed (Out)
• Joshua Dobbs – Gameday Inactive (Out)
• Dre Greenlaw – Achilles (Out)
• Yetur Gross-Matos – Knee (Out)
• Elijah Mitchell – Undisclosed (Out)
• Ben Bartch – Gameday Inactive (Out)
• Ambry Thomas – Forearm (Out)
• Talanoa Hufanga – Knee (Out)
• Aaron Banks – Calf (Questionable)
• Kalia Davis – Knee (Out)
• Drake Jackson – Knee (Out)
• Dee Winters – Ankle (Out)
• Darrell Luter Jr. – Gameday Inactive (Out)
• Ricky Pearsall – Back (Out)

Vikings Injury Report

• T.J. Hockenson – Knee (Out)
• Dalton Risner – Back (Out)
• Jordan Kunaszyk – Undisclosed (Out)
• Jeremy Flax – Undisclosed (Out)
• Gabriel Murphy – Undisclosed (Out)
• J.J. McCarthy – Knee (Out)
• Mekhi Blackmon – Knee (acl) (Out)
• NaJee Thompson – Knee (Out)
• Jordan Addison – Ankle (Questionable)

49ers Offense Breakdown

The 49ers’ offense put up 32 points in their 32-19 win over the Jets, racking up 24 first downs and 180 yards on the ground from 38 attempts. Brock Purdy threw for 221 yards, completing 65.5% of his passes, and was sacked three times. However, he didn’t throw any touchdowns. The offense was efficient on 3rd down, converting 46.2% of their chances.

Jordan Mason had a big game on the ground, rushing for 147 yards and averaging 5.2 yards per attempt, including a long run of 24 yards. Jauan Jennings led the receiving corps with 64 yards on five catches.

Vikings Offense Breakdown

Sam Darnold completed 79% of his passes for 208 yards and two touchdowns, leading the Vikings to a 28-6 win over the Giants. Darnold’s top target was Justin Jefferson, who had 59 yards receiving, including a 44-yard touchdown. The Vikings’ offense had 17 first downs and 201 yards passing, with Darnold throwing for two touchdowns and one interception.

On the ground, the Vikings rushed for 111 yards on 26 attempts, with Aaron Jones leading the way with 94 yards, averaging 6.7 yards per attempt and scoring one touchdown. The Vikings struggled on third down, converting only 30% of their chances, and Darnold was sacked once during the game.

49ers Team Defense

The 49ers’ defense gave up two passing touchdowns in their most recent game against the Jets, but they still came out on top with a 32-19 win. New York finished with 198 passing yards on 19 completions. San Francisco’s defense held the Jets to just 68 rushing yards on 19 attempts.

Overall, the 49ers allowed 266 total yards and forced one interception. They struggled to get off the field on third downs, allowing the Jets to convert 60% of their third down attempts. Additionally, the 49ers had only one sack in the game.

Vikings Team Defense

Minnesota’s defense was dominant in their 28-6 win over the Giants, allowing just 166 passing yards and forcing two interceptions. They limited New York to 240 total yards and held them to 3.5 yards per attempt on 21 rushes. The Vikings’ secondary was tough to crack, giving up only 4 yards per attempt and not allowing a passing touchdown.

Minnesota also recorded five sacks in the game and held the Giants to a 38.9% third-down conversion rate. They also won the battle in the trenches, with 10 more quarterback hits than the Giants and two tackles for loss.

49ers vs Vikings Trends

• Across the 49ers last ten road games, the team averaged 29 points per game while allowing 17. Their record vs the spread in these contests was 6-3-1, while going 7-3 straight-up.
• Through their last three home games, Minnesota has an ATS record of just 1-1-1. However, their overall record was 1-2 while averaging 24 points per game.
• In their last five games as the betting underdog, the Vikings have a straight up record of 1-4 and an ATS mark of 2-2-1.
• Across their last three matchups as the betting favorite, the 49ers have an overall record of 2-1 while going 1-2 against the spread.

49ers vs Vikings Prediction

Our pick vs. the spread is to take the Vikings to cover as home underdogs. They are currently sitting at -6 vs. the 49ers, and we have the Vikings winning this one 20-18.

For this week two matchup, we are also leaning towards taking the under, with a projected combined score of 38 points and the O/U line sitting at 45.5 points.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.