The Los Angeles Rams will face off against the Arizona Cardinals at 4:05 ET on Sunday, September 15th. This matchup is being played at State Farm Stadium in Glendale.

On the money line, the Cardinals are -121 as they host the Rams at 4:05 ET on Sunday, September 15th at State Farm Stadium in Glendale, AZ. The Rams are the slight favorite with a point spread of +1. The over/under line is at 49.5 points, and FOX is handling the television coverage of this week two NFC West matchup.

• Date: Sunday, September 15th
• Time: 4:05 ET
• Location: State Farm Stadium, Glendale
• TV: FOX

Rams vs Cardinals

The Rams’ most recent game was an overtime loss to the Lions, finishing 26-20 in favor of Detroit. Los Angeles went into the game as +5.5 point underdogs and lost straight-up and against the spread. The combined 46 points was short of the over/under line of 53.5 points.

After the Rams’ early 3-0 lead, the Lions scored 10 unanswered points heading into halftime. However, Los Angeles fought back in the 4th quarter, and with a 9-yard touchdown pass from Matthew Stafford to Cooper Kupp, they tied the game at 20. In overtime, the Rams were outscored 6-0.

The Cardinals’ 34-28 loss to the Bills saw them fall behind 24-10 in the 3rd quarter after Buffalo scored 14 unanswered points. Although Arizona made a late push in the 4th quarter, outscoring the Bills 11-10, it wasn’t enough to overcome the deficit. Arizona’s record is now 0-1 after this non-conference matchup, in which they were +6.5 point underdogs on the road. The combined 62 points easily surpassed the O/U line of 45.5 points.

Arizona started the game well, leading 7-0 after the 1st quarter and adding a field goal in the 2nd. However, Josh Allen and the Bills took over from there, with Allen finishing the game with 358 yards passing and five touchdowns. Arizona’s only 4th quarter touchdown came from a pass from Kyler Murray to Antoine Wesley.

Rams Injury Report

• KT Leveston – Ankle (Out)
• Alaric Jackson – Suspension (Out)
• Derion Kendrick – Acl (Out)
• Steve Avila – Knee (Questionable)
• Puka Nacua – Knee (Out)
• Tre Tomlinson – Undisclosed (Out)
• Conor McDermott – Undisclosed (Out)
• Darious Williams – Hamstring (Out)
• Joe Noteboom – Ankle (Questionable)
• Jimmy Garoppolo – Suspension (Out)
• Rob Havenstein – Ankle (Questionable)
• Tyler Higbee – Knee (Out)
• Larrell Murchison – Arm (Out)

Cardinals Injury Report

• Zay Jones – Suspension (Out)
• Jonah Williams – Knee (Questionable)
• Carter O’Donnell – Undisclosed (Out)
• BJ Ojulari – Knee (Out)
• Xavier Weaver – Oblique (Questionable)
• Elijah Jones – Ankle (Out)
• Christian Jones – Ankle (Out)
• Darius Robinson – Calf (Out)

Rams Offense Breakdown

In their 26-20 overtime loss to the Lions, the Rams’ offense totaled 26 first downs and 363 yards. Matthew Stafford threw for 317 yards (34/49), with one touchdown and one interception. He connected with Cooper Kupp 14 times for 110 yards and a touchdown. The running game struggled, with Kyren Williams managing only 50 yards on 18 carries and one touchdown.

The Rams’ offense was 41.7% on third down and allowed two sacks. Stafford’s passer rating was 85 in the loss.

Cardinals Offense Breakdown

In their 34-28 loss to the Bills, the Cardinals’ offense managed 18 first downs and 352 total yards. Kyler Murray led the team with 57 rushing yards, including a 29-yard run, and threw for 146 yards, completing 67% of his passes. He was sacked four times and finished with a passer rating of 91, throwing one touchdown.

Despite a good ground game that produced 124 yards on 25 attempts, the passing attack struggled, averaging just 4.7 yards per attempt. Greg Dortch was the leading receiver with 47 yards. Arizona also did well on third down, converting 53.8% of their chances.

Rams Team Defense

In their 26-20 overtime loss to the Lions, the Rams’ defense allowed 163 rushing yards on 31 attempts, including a 5.3 yards per attempt average. Despite this, they held the Lions to just 200 passing yards on 18 completions. The Rams’ defense also came up with one interception and allowed just one passing touchdown.

On third downs, the Rams allowed the Lions to convert 46.2% of their chances. Los Angeles also had two sacks in the game and 363 total yards.

Cardinals Team Defense

In their 34-28 loss to the Bills, the Cardinals’ defense gave up 222 passing yards on just 18 completions. Buffalo had a big day through the air, averaging 9.7 yards per attempt. Arizona’s defense struggled to stop the run, allowing 130 yards on 33 attempts. Despite allowing two passing touchdowns, the Cardinals’ defense held Buffalo to a 33.3% conversion rate on third down.

Arizona’s defense managed two sacks in the game and won the tackles for loss battle with a +1 differential. The Cardinals will be looking to tighten up defensively in their next game after allowing Buffalo to move the ball for 352 total yards.

Rams vs Cardinals Trends

• When looking at their past three road matchups, Los Angeles has an ATS record of 2-1 while averaging 21 per game. The team went 1-2 overall in these games.
• Across their last three home contests, Arizona has a 2-1 record vs the spread. Their overall mark in these games was 1-2, while averaging 26 points per game.
• Looking back on the team’s last three games as the underdog, the Rams have a straight up record of 1-2. Their record vs the spread in these games was 2-1.
• As the betting favorite, the Cardinals have an ATS mark of just 1-4 in their last five games. Arizona posted a straight up mark of 1-4 in these matchups.

Rams vs Cardinals Prediction

For this week two matchup between the Rams and Cardinals, we have the Cardinals coming out on top by a score of 26-21. This would make the Cardinals the best bet to cover the spread, as they are currently sitting at -1 point favorites at home.

As for the over/under, with the line at 49.5 points, we have a prediction of 47 combined points, making the under a good bet in this one.

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All odds are courtesy of Action247 Sportsbook. Good luck!!

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* All odds are provided by Action247 Sportsbook and all odds subject to change.**All views expressed are my own. My picks are my own and are not a guarantee, bet at your own risk.Action247 does not warrant the accuracy of completeness of the information, text, graphics, links or other items contained within these post.